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TIER 1 ORIGINAL PRODUCTS

Welcome to Tier 1 Origins

Tier 1 Origins was created to help every individuate find a more balanced sense of health and wellness.

As well as Lowering Blood Pressure, helping stabilize Blood Sugar levels in Diabetic Patients, Reducing Cholesterol, helping with getting a sound night sleep, Possibly Prevents infection from bacterial and viral infections, and has been shown throughout history to improve libido.

Feeling better is only a day away. Start the journey towards better health, vitality and wellness today.

Curcumin (just one of many components of Turmeric):
A Wonder Drug as a Preventive Measure for COVID19 Management
Turmeric – Curcumin It is reported that, curcumin exerts antiviral activities against broad spectrum of viruses including HIV, HSV-2, HPV viruses, Influenza virus, Zikavirus, Hepatitis virus and Adenovirus

Turmeric – Curcumin: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299138/

Cinnamon: extract has antiviral effects against SARS-CoV      https://www.ncbi.nlm.nih.gov/pmc/articles/P MC7146686/

Turmeric – Use of Curcumin in Depression Significant anti-anxiety effects were reported in trials, supporting the significant clinical ability of curcumin in correcting depressive symptoms. Notably, no adverse events were reported in any of the trials.

PTSD – BTBI
Turmeric/Curcumin Holds great promise as a therapeutic agent in alleviating fear and anxiety disorders characterized by persistent, unwanted memories. As well as impair either newly formed or reactivated fear memories in a widely studied animal model of traumatic memory formation in PTSD.
Turmeric – Curcumin: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367473/

Turmeric – Curcumin: https://pubmed.ncbi.nlm.nih.gov/28236605/

Anti-Inflammatory – TurmericGinger has been extensively studied for its ability as an anti-inflammatory, antioxidant, and its antihypertensive effects. Arthritis-related diseases were the most conducted studies, particularly osteoarthritis (OA). Ginger may also help in the management of exercise-induced inflammation and muscle soreness, thus enhancing recovery and performance in active people.

Turmeric: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299138/

Turmeric: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664031/

Ginger: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019938/

Turmeric – Curcumin’s antiviral and antibacterial activity has shown to act against various important human pathogens like the influenza virus, hepatitis C virus, HIV and strains of StaphylococcusStreptococcus, and Pseudomonas. Turmeric has a antiviral activity was observed against several different viruses including hepatitis viruses, influenza viruses and emerging arboviruses like the Zika virus (ZIKV) or chikungunya virus (CHIKV). Interestingly, it has also been reported that the molecule inhibits human immunodeficiency virus (HIV), herpes simplex virus 2 (HSV-2) and human papillomavirus (HPV), indicating that curcumin reduces the spread of sexually transmitted diseases.

Turmeric: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509173/

Turmeric and Ginger and Cinnamon in many studies both systolic and diastolic blood pressure reduced significantly during the 1st month of study and this reduction was sustained throughout follow up. These are some of the oldest and most widely used spices of the world, they are well documented for its antidiabetic and antihypertensive, anti- inflammatory, anticancer roles have been established in modern studies. Turmeric  Ginger and Cinnamon are a source for preventive and therapeutic agents for the management of diabetes and related disorders. The antihypertensive capacities of turmeric rhizome revealed in this research highlighted its potential to serve as a source for preventive and therapeutic agents for the management of diabetes and related disorders.

Cinnamon: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745724/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252471/

Curcumin has been reported to modulate growth factors, enzymes, transcription factors, kinase, inflammatory cytokines, and proapoptotic (by upregulation) and antiapoptotic (by downregulation) proteins. This polyphenol compound, alone or combined with other agents, could represent an effective drug for cancer therapy.

Turmeric: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835707/

Alzheimer’s DiseaseTurmeric and Ginger evidence indicates due to various effects of Curcumin and Ginger that patients with Alzheimer’s Disease memory and focus has improved.

Turmeric: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781139/

Turmeric:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744901/

Turmeric, Ginger in terms of obesity-related cardiovascular risk factors, ginger was reported to be beneficial in lowering the risk factors, such as antiobesity, antidiabetic, antinausea body fat mass, body fat percentage, total cholesterol, waist circumference, waist-to-hip ratio, and insulin resistance. Cinnamon has anti-microbial, anti-parasitic, anti-oxidant and free radical scavenging properties. In addition CZ seems to lower blood glucose, serum cholesterol and blood pressure, suggesting beneficial cardiovascular effectsNutmeg Taken together, nutmeg extract may increase muscle mass or prevent decrease of muscle wasting in soleus muscle by partly stimulating myogenesis, regeneration process, and preserving muscle mass

Ginger https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019938/

Ginger https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616534/

Cinnamon: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854496/

Nutmeg: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311876/

Muscle Fatigue – Pain Reduction

Turmeric: aids in the management of oxidative and inflammatory conditions, metabolic syndrome, arthritis, anxiety, and hyperlipidemia. It may also help in the management of exercise-induced inflammation and muscle soreness, thus enhancing recovery and performance in active people.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664031/

Anti-Inflammatory

Turmeric has been extensively studied for its role in the regulation of RAAS (renin–angiotensin–aldosterone system) components through which it is known to exert anti-oxidant, anti-inflammatory and antihypertensive effects.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299138/

Ginger – Arthritis-related diseases were the most conducted studies, particularly osteoarthritis (OA). Regarding OA, six studies investigated the efficiency of the constituents of ginger that serve as anti-inflammatory agents.

Turmeric and Covid 19 Management

Curcumin (just one of many components of Turmeric):
A Wonder Drug as a Preventive Measure for COVID19 Management
In the context of preventive and supportive therapy, several polyphenolic compounds extracted from natural products were identified with varied antiviral mechanisms such as targeting virus host specific interactions, viral entry, replication, and assembly. In line with these findings, curcumin, is one of the natural compounds that had been widely investigated for its antiviral effects [4]. Curcumin, exhibits wide range of therapeutic properties including antioxidant, anti-microbial, anti-proliferative, anti-inflammatory, neuroprotective and cardioprotective properties. It is reported that, curcumin exerts antiviral activities against broad spectrum of viruses including HIV, HSV-2, HPV viruses, Influenza virus, Zikavirus, Hepatitis virus and Adenovirus

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299138/

Cinnamon extract has antiviral effects against RNA viruses. Zuang et al. showed that cinnamon extract inhibited wild-type SARS-CoV in vitro with an IC50 of 43 µM [8]. The possible proposed mechanism of action was by blocking cell entry via endocytosis.
https://www.ncbi.nlm.nih.gov/pmc/articles/P MC7146686/

Boosts Immunity
Curcumin’s antiviral and antibacterial activity was investigated, and it was shown to act against various important human pathogens like the influenza virus, hepatitis C virus, HIV and strains of Staphylococcus, Streptococcus, and Pseudomonas.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509173/

Anxiety/Depression

Turmeric
https://pubmed.ncbi.nlm.nih.gov/28236605/

Clinical Use of Curcumin in Depression: A Meta-Analysis

Introduction: There is growing interest in the use of curcumin, a plant polyphenol with potent anti-inflammatory, anti-oxidant, and neuroprotective properties, as a novel antidepressant. Clinical trials have yielded conflicting conclusions pertaining to its effectiveness in depression. A meta-analysis of the topic, which has not been done until now, is therefore necessary to summarize current evidence and generate hypotheses for further research.

Results: Six clinical trials with a total of 377 patients were reviewed, comparing the use of curcumin to placebo. In patients with depression, the pooled standardized mean difference from baseline Hamilton Rating Scale for Depression. Significant anti-anxiety effects were also reported in 3 of the trials, support the significant clinical efficacy of curcumin in ameliorating depressive symptoms. Notably, no adverse events were reported in any of the trials. Most trials had a generally low risk of bias, except for an open trial of curcumin and a single-blinded study.

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